Custom peptide synthesis
Your sequence, synthesised to specification.
Peptamer plans and produces custom research peptides from milligram to gram scale, with selectable purity, modification options and analytical documentation for every project.
How a custom project moves forward
Each project follows the same controlled sequence, from the first sequence review through to a documented, packed batch.
- 01
Sequence review
Confirm the target sequence, quantity, purity target, modifications and delivery format.
- 02
Feasibility evaluation
Assess sequence length, hydrophobicity, difficult couplings and any disulfide bonds before production begins.
- 03
Synthesis
Build the confirmed sequence at the agreed scale, from milligram quantities up to gram-scale batches.
- 04
Purification
Purify the crude material by HPLC toward the agreed purity target.
- 05
Analytical review
Confirm purity and identity by RP-HPLC and mass spectrometry before the batch is reported as complete.
- 06
Final preparation and packing
Complete lyophilisation or formulation, prepare documentation and pack the batch for shipment.
Built around your specification
Every project is scoped individually, so the options below are starting points for discussion rather than fixed defaults.
Milligram to gram scale
Projects are scoped from small feasibility batches up to gram-scale production runs.
Selectable purity
Purity targets of approximately 95%, 98% or 99% can be discussed and confirmed for each sequence.
Modification support
Terminal groups, cyclisation, labelling and other modifications are reviewed for feasibility per project.
Powder or solution
Finished material can be discussed as lyophilised powder or as a formulated solution.
Confidential handling
Submitted sequences and project details are handled in confidence throughout review and production.
Analytical documentation
Each batch is supported by a project-specific report summarising the analytical review.
Specify your peptide
Share as much of the specification below as you have; anything undecided can be discussed during feasibility review.
| Parameter | Options | Notes |
|---|---|---|
| Length | Short fragments to longer sequences | Reviewed for feasibility, including difficult couplings and disulfide bonds |
| Scale | Milligram to gram | Confirmed per project after feasibility review |
| Purity | Approximately 95%, 98% or 99% | Final target confirmed on quotation |
| Modifications | Terminal groups, cyclisation, labelling and others | Availability reviewed per sequence |
| Counter-ion | Discussed where relevant to the sequence | Confirmed in the batch documentation |
| Format | Lyophilised powder or solution | Selected according to the research use |
| Analysis | RP-HPLC and mass spectrometry | Summarised in the project report |
Why researchers bring their sequence to Peptamer
Custom synthesis works best when the specification is clear and the review process is transparent. Peptamer keeps the sequence, the feasibility notes and the analytical results aligned from the first enquiry through to the final report.
- A feasibility review before any production commitment
- Purity, modification and format options confirmed per project
- An analytical report accompanying every finished batch
- Confidential handling of submitted sequences throughout
| RP-HPLC | ≥95–99% |
|---|---|
| MS | [M+H]⁺ |
| Scale | mg → g |
| Format | powder · solution |
Custom synthesis, answered
What information do you need to start a project?
A target sequence or name, the required quantity, a purity target and any modification or format preferences. Missing details can be discussed during feasibility review.
What scale can a custom project cover?
Projects are typically scoped from milligram quantities for early feasibility work up to gram-scale batches, depending on the sequence.
What purity targets are available?
Targets of approximately 95%, 98% and 99% can be discussed; the practical target for a given sequence is confirmed after feasibility review.
Can you make modified peptides?
Modification requests, such as terminal groups, cyclisation or labelling, are reviewed individually and confirmed on inquiry, since feasibility depends on the sequence.
Ready to scope your peptide?
Send your sequence and target specification, and we will confirm what is practical during feasibility review.
Start a project